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Top 10 MR stories of the year

December 21, 2022
MRI
From the November 2022 issue of HealthCare Business News magazine

11.74T MR scanner could be operational by end of 2022

Researchers at Gachon University Gil Medical Center (GUGMC) in South Korea and MR components developer ASG Superconductors in Italy announced in November they were optimistic about unveiling the world’s first simultaneous multi-channel/multi-nuclear 11.74T MR scanner before the year is out.

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The solution will be used primarily for brain imaging research and is expected to be powerful enough to acquire images that are almost 10 times more detailed than those of 1.5T MR scanners.

"The ultra-high resolution brain images obtained from the 11.74T MR system are expected to provide significant clues for the early diagnosis and treatment of neuro-degenerative brain diseases such as Parkinson's disease, Alzheimer's and stroke,” said professor Woo-Kyung KIM, president of Gachon University Gil Medical Center (president of the Neuroscience Research Institute), in a statement.

Among its achievements was satisfying the three main criteria of the Site Acceptance Test in the first half of 2022. This includes having an internal temperature of <2.2 Kelvin, a magnetic field intensity of 2.2K, and magnetic field uniformity.

Technical managers of ASG and experts from Korea carried out the test. The evaluation committee confirmed the magnetic field reached the target field density and maintained stability and uniformity.

The magnet was manufactured in December 2018. The researchers plan to combine the 11.74T magnet with gradient magnetic coils, RF coils, electronic components and power supplies when they start using it.

The scanner is fully serviced by ASG technicians on site and is supported by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health and Welfare, Korea.

Several MR systems more powerful than standard 1.5T and 3T scanners and even the top-end 7T scanners are in the works. In 2017, the Weizmann Institute of Science in Israel installed Bruker’s Biospec 15.2T USR preclinical ultrahigh-field MR system to give clinicians a better understanding of biomolecular processes of certain diseases, as well as advanced biomaterials that could potentially impact a variety of emerging diagnostic and therapeutic approaches.

"[This] instrument will enable new forms of multiplexed imaging not previously available to the institute, with the aim to develop, optimize and implement genetically engineered reporter systems for MR with artificial 'multicolor' characteristics," Dr. Amnon Bar-Shir of the department of organic chemistry at the institute, told HCB News at the time.
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Steven Ford

Possible problems with this study

March 08, 2023 12:47

The study was partially sponsored by the manufacturer of the ultra low field MRI and some of the physicians were investors in that company. This alone does not mean that the study is invalid.

The study you cite DOES NOT show that the low field MRI is nearly as effective as high field MRI in diagnosing stroke. Most importantly, the patients imaged in the ULF scanner had already been diagnosed with a stroke before imaging a second time with the low field machine. A more rigorous study would use a double-blind process.

Secondly, some of the patients were previously imaged using CT, not MRI. This is the very definition of an apples to oranges comparison.

The MRI scanner in question has limited resolution compared with virtually every MRI in the USA, even 20-year old scanners. It cannot image very small tumors or bleeds.

Finally, the study states that about 80% of the strokes were correctly identified. A more accurate headline would be 'ULF MRI leads to correct diagnosis 80% of the time' or 'ULF MRI Better Than Nothing'. More critically but more accurately, 'ULF MRI is a Poor Alternative if You Have Another Choice'.

A more meaningful study would compare low-cost CT scans to the use of this innovative and clever scanner, because they are more readily available and less costly.

This study has anecdotal value.

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