For Sale WATERS Acquity UPLC Chromatograph

For Sale Waters Acquity UPLC H-Class Liquid Chromatography System with QDa & TUV Detectors

Pre-owned instrument

• Fully Functional
• Current model
• Serviced & in Stock
• Good cosmetic condition
• Warranty

Here is what you will receive:
• Waters Acquity UPLC H-Class Quaternary Solvent Manager (model #186015018)
• Waters Acquity UPLC H-Class Sample manager FTN with 50uL sample loop (model #186015017)
• Waters Acquity UPLC Column Manager (model #186015043)
• Waters Acquity TUV Detector w/UPLC analytical flow cell 500nL (model #186015031)
• Waters Acquity QDa Detector (model #186008511)
• Solvents Tray
• PC with Empower 3 software
• Inter-communication cables
• Standard power cords

Please Note: The computer and Empower 3 software came to us with this Waters system. If the user’s application requires additional licenses, the end user will need to purchase them from Waters.

Waters Acquity UPLC H-Class Liquid Chromatography System Configuration:
• Dwell volume: <400 uL (standard 100 uL mixer)
• Integrated leak management: leak sensors, as standard, and safe leak handling
• Quantum synchronization: injection synchronization between the pump and sample manager enhances retention time reproducibility
• Settable flow rate range: 0.001 to 2.200 mL/min in 0.001 mL increments
• Maximum operating pressure: 15,000 psi up to 1.0 mL/min, 7800 psi up to 2.2 mL/min
• pH range: 2 to 12
• Unattended operation: leak sensors and safe leak handling, full 96-hour diagnostic data display through console software
• Cycle time: <30 s inject-to-inject

Acquity UPLC H-Class Quaternary Solvent Manager:
• Number of solvents: blend up to four solvents in any combination
• Solvent degassing: integrated vacuum degassing, four chambers; one additional chamber for the SM-FTN purge solvent
• Solvent blending: automated, on-line pH, ionic strength, and organic modifier blending from pure solvents with Auto-Blend Plus Technology
• Gradient formation: low-pressure mixing, quaternary gradient
• Gradient profiles: 11 gradient curves [including linear, step (2), concave (4), and convex (4)]
• Primary check valve: intelligent Intake Valve (i2 Valve)
• Flow accuracy: ±1.0% at 0.5 to 2.0 mL/min using 100% A (with i2 Valve); back pressure 600 to 1000 psi with degassed H20
• Flow precision: 0.075% RSD or ±0.020 min SD, whichever is greater, based on six replicates (with i2 Valve)

Acquity UPLC H-Class Sample Manager FTN:
• Injection volume range: 0.1 to 50 uL, up to 1,000.0 uL with optional extension loops
• Accuracy (aspiration): ±0.2 uL, measured by fluid weight removed from vial with 10.0 uL injections averaged over 20 injections using a standard 100 uL syringe.
• Precision: <1% RSD 0.2 to 1.9 uL; <0.5% RSD 2.0 to 10.0 uL
• Number of sample plate positions: Two
• Compatible labware: 96 and 384 microplates, 48 position 2.00-mL vial plates, 48 position 0.65-mL micro-centrifuge tube plates, 24 position 1.50-mL micro-centrifuge tube plates
• Maximum sample capacity: 768 in two 384-well plates or, 96 in 2-mL vial holders
• Sample compartment: 4 to 40 DegC, settable in 0.1 DegC increments
• Temperature accuracy: ±0.5 DegC at sensor
• Temperature stability: ±1.0 DegC at sensor
• Injection needle wash: integral, active, programmable
• Minimum sample required: 3 uL residual, using total recovery; 2 mL vials (zero offset)
• Sample carryover: <0.004% caffeine (UV); <0.005% sulfadimethoxine (MS)
• Advanced Sample Manager capabilities: auto-dilution, auto-addition, and load-ahead

Acquity UPLC Column Manager:
• Column capacity: 2 columns (max. length of 150 mm with filter or guard column) or 4 columns (max. length of 50 mm) with optional tubing kit, up to 4.6 mm (I.D.)
• Switching valves: 2 nine-port, eight-position valves; provides programmable, automatic, random access switching, waste and bypass positions for rapid solvent changeover
• Column compartment temperature range: 4.0 to 90.0 DegC, settable in 0.1 DegC increments; 2 independent heat/cool zones per module, up to six zones in a stacked configuration
• Column compartments temperature accuracy: ±0.5 DegC
• Column compartments temperature stability: ±0.3 DegC
• Solvent conditioning: active pre-heating as standard

Acquity UPLC TUV Detector:
• Wavelength range: 190 to 700 nm
• Wavelength accuracy: ±1 nm
• Sampling rate: up to 80 points/s
• Light source: deuterium lamp
• Dispersion volume: ≤0.8 uL (Analytical flow cell);
• Flow cell design: light-guiding UPLC intelligent technology flow cell
• Path length: 10 mm (analytical flow cell)
• Flow cell volume: 500 nL (analytical flow cell)
• Pressure limit: 1000 psi (all flow cells)
• Optical bandwidth: 5 nm

Acquity UPLC QDa Detector:
• Acquisition modes: Full scan MS, Selected Ion Recording (SIR)
• RADAR: collect highly specific quantitative data for target compounds with the ability to visualize all other components
• Mass range: 30 to 1250 m/z
• Scan speed: automatically optimized for enhanced data quality for acquisition rates of up to e.g. 10Hz for m/z 100 to 1000 or 20 Hz for m/z 50 to 500
• Mass accuracy: mass accuracy is better than ±0.2 Da over the full mass range
• Mass stability: mass drift is less than 0.1 Da over a 24-hour period
• Linearity of response: the linearity of response relative to sample concentration for a specified compound is up to four orders of magnitude from the limit of detection
• Ion polarity switching time: 25 ms to switch between positive and negative ion modes
• SIR acquisition rate: automatically-optimized for enhanced data quality for acquisition rates of up to 100Hz
• Number of SIR channels: up to 1024 SIR channels (32 functions, 32 channels per function) can be monitored in a single acquisition
• Mass resolution: automated mass resolution control (0.7 Da) for constant data quality

Customization/Options:
• Other detectors and flow cell options might be available. Please inquire with our sales team.

Testing performed by our in-house service team:
The Waters Acquity UPLC H-Class Liquid Chromatography System with QDa & TUV Detectors passed all tests and was found to be fully functional:
• We inspect the Waters Acquity UPLC H-Class Liquid Chromatography System for its physical condition.
• We check for seamless communication with the Empower software.

Quaternary solvent manager:
• We carefully evaluate the system's startup process for proper functionality.
• We thoroughly assess the stability and consistency of solvent delivery.
• We evaluate the system's performance in creating and running gradient tests.
• We perform a gradient proportioning valve test to confirm accurate gradient composition.
• We run a seal-washing pump test to assess the functionality of the seal-washing system.
• We test the leak sensor.
• We perform the degasser health check to ensure proper degassing of solvents.
• We test the pressure limiter to validate the pressure regulation capabilities.
• We verify the accuracy of flow rates.
• We run leak tests to check for leaks under high-pressure conditions.

Sample manager FTN:
• We power on and ensure the proper initialization of the sample manager.
• We carry out a sample cooler set temperature accuracy test to ensure precise temperature control.
• We do a syringe leak test to detect any leaks in the syringe system that could affect sample delivery.
• We perform the needle seal test.
• We test the leak sensor.
• We perform a reproducibility test to assess the reproducibility of sample handling and injection.

Column manager:
• We power on and ensure the proper initialization of the column manager.
• We perform a column oven temperature accuracy test to verify the accuracy of temperature control in the column oven.

TUV Detector:
• We power on and ensure the proper initialization of the TUV detector.
• We check the remaining lamp life to ensure optimal performance.
• We run tests to verify accurate and reliable detection capabilities.
• We verify the leak sensor.

QDa Detector:
• We check the detector initializes correctly, establishing its baseline functionality and readiness for operation.
• We run tests to verify accurate and reliable detection capabilities.
• We run calibration to verify the accuracy and reliability of the detector's measurements.
• We test the detector's ability to distinguish between closely spaced peaks, which is important for accurately identifying and quantifying compounds.
• We run resolution checks.

Instrument Overview:
• The Waters Acquity UPLC H-Class Liquid Chromatography System is a high-performance instrument for analytical separations and quantification.
• It is equipped with QDa and TUV detectors, offering sensitive detection and reliable UV-Vis measurements.
• The system is designed for efficiency, delivering high-resolution separations and short analysis times.
• It provides flexibility and versatility for a wide range of analytical challenges.
• The Waters Acquity UPLC H-Class is a dependable choice for laboratories requiring accurate chromatographic analysis.

Instrument Application: Waters Acquity UPLC H-Class Liquid Chromatography System with QDa & TUV Detectors
The Waters Acquity UPLC H-Class Liquid Chromatography System is commonly used in various chromatographic analysis and detection applications. including:
• Pharmaceutical analysis: for drug discovery, development, and quality control.
• Environmental analysis: for monitoring contaminants in water, soil, and air samples.
• Food and beverage analysis: for detecting additives, pesticides, and contaminants in food products.
• Clinical research: for analyzing biomarkers, metabolites, and pharmaceutical compounds in biological samples.
• Chemical research: for characterizing organic compounds and investigating reaction kinetics.

The key features of Waters Acquity UPLC H-Class Liquid Chromatography System:
• High-performance analytical separations and quantification.
• Sensitive detection with QDa and TUV detectors.
• Efficient with high-resolution separations and short analysis times.
• Flexibility for various analytical challenges.

Why should you buy from us?

Our Advantage
• We have experience servicing and repairing these instruments.
• This instrument goes through all the described service steps before shipping.
• We offer detailed photos and videos of the instruments you buy.
• We are an approved pre-owned equipment vendor to many large US, Canadian, and EU Universities.
• We are an approved pre-owned equipment vendor to many Fortune 500 US and International Biopharma companies.
• Many upgrade and repair parts are in stock.
• On-site installation may be available in the Boston Area (New England area)
• US or International shipping is no problem (see the shipping tab on how we pack and feel at ease)

Our Guarantee
• It will work!
• Warranty
• Smooth process from the initial quote to order fulfillment.
• Customer references are available.

This will ship via freight. Please contact us with your zip code to obtain a shipping quote.
*ME* Medium Crate
450#

PLEASE NOTE THAT THE QUESTIONS BELOW ARE ANSWERED IN MORE THOROUGH DETAIL ON OUR WEBSITE

Q: Can I view this instrument in person at your facility or do a live Zoom demo before it is shipped to me?
A: We can accommodate both in-person or Zoom demos.

Q: What about the warranty?
A: The instrument comes fully warranted for both parts and labor.

Q: Do you offer installation, service, etc?
A: We offer remote installation and training packages to familiarize you with this instrument.

Q: What should I watch out for when buying a used/pre-owned instrument from another lab?
A: Ensure that the instrument is in good working condition with no damage or wear that could affect its performance. Ask for details about testing steps performed, video demo, and test screenshots.

Q: Do you have more than one of these instruments on hand?
A: We generally carry multiple instruments on hand, along with a variety of spare parts.

Q: This procurement is for a University or College. Are purchase orders with NET terms accepted?
A: We accept purchase orders from all major US and Canadian universities.

Q: How fast will you ship?
A: We can ship within a few days to two weeks. Shipping time depends on the current demand for our instruments. Members of our sales team will be able to offer current delivery estimates.

Q: Will my instrument be insured during shipping?
A: Absolutely! We insure all our shipments as long as we are the shipper. If a customer ships on their account, they handle insurance.

Q: How do you pack? Have you previously packed and shipped the fragile laboratory instruments?
A: We have extensive experience shipping high-end and complex laboratory instruments in the US and Internationally.

Q: Do you ship Internationally?
A: Yes! We have shipped to multiple continents and over 30 countries.

Q: How much will I save buying it pre-owned, and is it worth it?
A: When compared to buying a new instrument, you will save 60% or more and have plenty of funds left over for an additional instrument or two.

TO VIEW ADDITIONAL PHOTOS, VIDEOS AND VERY DETAILED INFORMATION SUCH AS TEST STEPS PERFORMED, CONFIGURATION, ETC., PLEASE VISIT OUR WEB SITE. TO GET THERE PLEASE CLICK ON “WEBSTORE”; TO YOUR RIGHT AND YOU WILL SEE LINK TO OUR SITE IN THE MIDDLE OF THE SCREEN. THEN USE LAST 5 DIGITS OF MPN NUMBER IN THE SEARCH FIELD TO LOCATE YOUR ITEM.

DO NOT HESITATE TO CALL US OR EMAIL US WITH ANY QUESTIONS YOU MIGHT HAVE.

ALL OF OUR ITEMS ARE AVAILABLE FOR INSPECTION AT OUR FACILITY.

Return Policy

Items are sold as-is with no returns or refunds available unless explicitly stated.